[1]祁爱英,陈玉辉.老年营养风险指数与结直肠癌病人术后感染性并发症的相关性分析[J].肠外与肠内营养杂志,2023,(06):347-350.[doi:10.16151/j.1007-810x.2023.06.005]
　QI Ai-ying,CHEN Yu-hui.Analysis of the association between geriatric nutritional risk indices and postoperatively infectious complications in elderly patients with colorectal cancer[J].PARENTERAL & ENTERAL NUTRITION,2023,(06):347-350.[doi:10.16151/j.1007-810x.2023.06.005]
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老年营养风险指数与结直肠癌病人术后感染性并发症的相关性分析()
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2023年06期
页码:
347-350
栏目:
论著
出版日期:
2023-12-10

文章信息/Info

Title:
Analysis of the association between geriatric nutritional risk indices and postoperatively infectious complications in elderly patients with colorectal cancer
作者:
祁爱英; 陈玉辉
解放军总医院第一医学中心普通外科医学部，北京 100853
Author(s):
QI Ai-ying;  CHEN Yu-hui
The First Medical Center of the PLA General Hospital, Medical Department of General surgery, Haidian, Beijing, 100853 China
关键词:
老年营养风险指数 ; 结直肠癌 ; 感染性并发症
Keywords:
Geriatric nutritional risk index;  Colorectal cancer;  Infectious complication
分类号:
R459.3，R574
DOI:
10.16151/j.1007-810x.2023.06.005
文献标志码:
A
摘要:
目的：探讨老年营养风险指数(GNRI)与结直肠癌病人术后感染性并发症的相关性。 方法：自2020年6月至2021年12月，回顾性收集解放军总医院第一医学中心收治的结直肠癌病人571例，根据病人术后是否发生感染性并发症，将病人分为感染组(n = 67)和对照组(n = 504)，比较两组病人临床特征，分析GNRI对结直肠癌病人术后感染性并发症的预测价值，同时分析结直肠癌病人术后感染性并发症的危险因素。 结果：与对照组比较，感染组病人GNRI水平显著降低[(93.71 ± 8.45) vs. (97.12 ± 3.89), P < 0.001]；感染组接受术前化疗的病人比例显著增高(8.96% vs. 3.37%, P = 0.029)。GNRI对结直肠癌病人术后不发生感染性并发症具有一定预测价值，曲线下面积为0.652(95%可信区间：0.567 ~ 0.737)。GNRI ≤ 98和接受术前化疗是结直肠癌病人术后感染性并发症的独立危险因素(P < 0.05)。 结论：GNRI降低与结直肠癌病人术后发生感染性并发症有关，给予适当的营养治疗。
Abstract:
Objective: To explore the correlation between the geriatric nutritional risk index (GNRI) and postoperatively infectious complications in elderly patients with colorectal cancer. Methods: A total of 571 elderly patients with colorectal cancer who admitted to the First Medical Center of the PLA General Hospital between June 2020 and December 2021 were retrospectively collected. Based on whether the patients developed postoperative infectious complications or not, they were divided into two groups: infected (n = 67) and control groups (n = 504). The predictive value of GNRI for presence of postoperatively infectious complications in the patents was evaluated and the risk factors for it were also identified. Results: Compared with the control group, the GNRI in the infected group were significantly lower [(93.71 ± 8.45) vs (97.12 ± 3.89), P < 0.001]. By contrast, the proportion of elderly patients receiving preoperativechemotherapy in the infected group significantly higher than in the controls (8.96% vs. 3.37%, P = 0.029). GNRI was useful in predicting the presence of postoperatively infectious complications in colorectal cancer patients, with an area under the curve of 0.652 (95% confidence interval: 0.567 ~ 0.737). Lower GNRI (score ≤ 98) and preoperative chemotherapy were independent risk factors for postoperatively infectious complications in elderly patients with colorectal cancer (P < 0.05). Conclusion: The lowered GNRI is associated with postoperatively infectious complications, providing evidence for the importance of enhanced nutritional support in elderly patients with colorectal cancer.

参考文献/References:


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备注/Memo

备注/Memo:
作者简介 ：祁爱英，主管护师，主要从事胃肠疾病方面的研究。E-mail：qiay79@163.com通讯作者 ：陈玉辉，E-mail：cyhnju@sina.com
更新日期/Last Update: 1900-01-01