[1]詹 贞,潘 杨.脑白质疏松(LA)病人Fazekas分级与营养状况的相关性分析[J].肠外与肠内营养杂志,2022,(06):337-341.[doi:10.16151/j.1007-810x.2022.06.003]
 ZHAN Zhen,PAN Yang.Correlation between Fazekas grading and nutritional status in patients with leukoaraiosis (LA)[J].PARENTERAL & ENTERAL NUTRITION,2022,(06):337-341.[doi:10.16151/j.1007-810x.2022.06.003]
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脑白质疏松(LA)病人Fazekas分级与营养状况的相关性分析
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2022年06期
页码:
337-341
栏目:
论著
出版日期:
2022-11-10

文章信息/Info

Title:
Correlation between Fazekas grading and nutritional status in patients with leukoaraiosis (LA)
作者:
詹 贞潘 杨
南京医科大学附属脑科医院 老年医学科,江苏南京 210029
Author(s):
ZHAN Zhen PAN Yang
Department of Geriatrics, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China
关键词:
脑白质疏松 营养指标 营养风险 危险因素
Keywords:
Leukoaraiosis Nutritional indicator Nutritional status Risk factors
分类号:
R743.34
DOI:
10.16151/j.1007-810x.2022.06.003
文献标志码:
A
摘要:
目的:探讨脑白质疏松(LA)病人Fazekas分级与相关营养状况的关系。 方法:回顾性研究2020年1月至2022年1月南京医科大学附属脑科医院神经内科收治的100例住院病人,根据Fazekas分级将脑白质疏松病人分为对照组LA0,(n = 30例),LA1(n = 28例),LA2(n = 24例)和LA3(n = 18例)。并对4组病人的基本信息(性别,年龄,BMI,吸烟和饮酒情况),临床资料,营养指标(ALB、PA、RBP)及营养状态(NRS 2002评分)进行统计分析。 结果:LA分级越高,营养指标呈下降趋势(P < 0.05);LA病人严重程度升高,病人的同型半胱氨酸氨酸水平呈升高趋势(P < 0.05)。LA等级越高,MMSE和MoCA的评分越低,认知功能障碍越严重(P < 0.05)。LA分级越高存在营养风险越多(P < 0.05)。 结论:LA病人的营养指标与LA严重程度相关,同时LA病情越严重,LA病人认知功能障碍越严重,并且营养风险越多。
Abstract:
Objective: To investigate the correlation between Fazekas grading and nutritional status in patients with leukoaraiosis (LA). Methods: Retrospective study. 100 inpatients in the Department of Neurology of Nanjing Brain hospital from January 2020 to January 2022 were selected. According to Fazekas classification, patients with leukoaraiosis were divided into control group LA0, (n = 30 cases), LA1 (n = 28 cases), LA2 (n = 24 cases) and LA3 (n = 18 cases). The basic information (gender, age, BMI, smoking and drinking), clinical data, cognitive impairment assessment (MMSE and MOCA score) and nutritional risk screening (MNA score) of the four groups were statistically analyzed. Results: As the grading of LA climbed, the nutritional indicators showed a downward trend (P < 0.05), and the level of homocysteine in patients rose (P < 0.05). The higher the LA level was, the lower the scores of MMSE and Moca were, and the more serious the cognitive impairment became (P < 0.05). The nutritional status deteriorated as the LA grading mounted. (P < 0.05). Conclusion: The nutritional indicators of LA patients are related to the severity of LA. At the same time, the more serious the condition of LA is, the more severe the cognitive dysfunction of LA patients is, and the more risky their nutritional statuses become.

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备注/Memo

备注/Memo:
基金项目 :国家自然科学基金青年项目(82101332) 作者简介 :詹 贞,副主任医师,医学硕士,主要从事运动障碍和营养方面的临床研究。E-mail:418052071@qq.com 通讯作者 :潘 杨,E-mail:neuro_panyang@163.com
更新日期/Last Update: 1900-01-01