[1]邢桂枚,谢 璞,李 敏,等.探讨腰大肌指数对重症急性胰腺炎病人营养风险评估及预后判断价值[J].肠外与肠内营养杂志,2022,(02):110-115.[doi:DOI : 10.16151/j.1007-810x.2022.02.010]
 XIN Gui-mei,XIE Pu,LI Min,et al.Investigate the value of psoas major index in evaluating nutritional risk and early prognosis of patients with severe acute pancreatitis[J].PARENTERAL & ENTERAL NUTRITION,2022,(02):110-115.[doi:DOI : 10.16151/j.1007-810x.2022.02.010]
点击复制

探讨腰大肌指数对重症急性胰腺炎病人营养风险评估及预后判断价值
分享到:

《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2022年02期
页码:
110-115
栏目:
论著
出版日期:
2022-03-10

文章信息/Info

Title:
Investigate the value of psoas major index in evaluating nutritional risk and early prognosis of patients with severe acute pancreatitis
作者:
邢桂枚1谢 璞2李 敏1王润东1花本菊1明 静1
安徽省第二人民医院,1.普通外科;2.CT室,安徽合肥 230041
Author(s):
XIN Gui-mei1 XIE Pu2 LI Min1 WANG Run-dong1 HUA Ben-ju1 MING Jing1
1. Department of General Surgery;2. Department of Computer Tomography Room;Anhui No. 2;Provincial People's Hospital, Hefei 230041, Anhui, China
关键词:
腰大肌指数 急性重症胰腺炎 营养风险评估 预后价值
Keywords:
Psoas major index Acute severe pancreatitis Nutritional risk assessment Prognostic value
分类号:
R459.3,R657.5+1
DOI:
DOI : 10.16151/j.1007-810x.2022.02.010
文献标志码:
A
摘要:
目的:探讨腰大肌指数(PMI)对重症急性胰腺炎(SAP)病人发生营养风险的评估及预后的判断价值。 方法:回顾性分析安徽省第二人民医院普通外科 2014年 1月 1日至 2021年 11月 31日收治的 81名 SAP病人。调取病人腹部 CT影像资料并采集病人第 3腰椎水平腰大肌截面积,计算 PMI。将 PMI的下四分位(P25)值作为临界点划分低 PMI组(< P25)与常规 PMI组(≥ P25),观察两组病人的一般基线情况及预后等差异。调取病人营养风险筛查资料,将营养风险筛查(NRS 2002)评分≥ 3分的病人纳入有营养风险组,< 3分纳入非营养风险组。运用 Pearson分析 PMI与营养风险发生的相关性。采用 Logistic回归分析 SAP病人发生营养风险的相关因素。 结果:两组病人一般资料比较未见明显差异(P > 0.05)。低 PMI组病人血红蛋白、白蛋白、前白蛋白水平明显低于常规 PMI组,第 7 天急性生理与慢性健康评分(APACHE II评分)及序贯器官衰竭评分(SOFA评分)明显高于常规 PMI组(P < 0.05)。低 PMI组病人胰腺感染性坏死、肺炎、多器官功能障碍(MODS)发生率较常规 PMI组高,ICU住院时间较常规 PMI组延长(P < 0.05)。 相关性分析显示,病人 PMI 值与营养风险评分呈负相关关系(r = -0.677,P = 0. 000)。多因素Logistic回归分析结果提示前白蛋白及白蛋白水平降低、APACHE II(7d)评分升高及 PMI值降低是 SAP病人发生营养风险的独立危险因素。 结论:PMI用于 SAP病人营养风险评估及预后的判断有一定价值。
Abstract:
Objective: To investigate the value of psoas major index (PMI) in evaluating nutritional risk and early prognosis of patients with severe acute pancreatitis (SAP). Methods: From January 1, 2014 to November 31, 2021,the Clinical Data of 81 SAP patients in anhui No. 2 provincial People’s hospital were analyzed retrospectively. The CT imaging system was used to collect the sum of psoas major cross-sectional area of the third lumbar spine and calculate PMI. The lowest quartile (P25) of the PMI was selected as the critical point to divide the low PMI group (< P25) and the normal group (≥ P25) . Compare the baseline situation and prognosis of two groups. The Nutritional risk screening scale (NRS 2002) was used to evaluate the nutritional risk of SAP patients and the patients with total score ≥ 3 points were included in nutritional risk group, < 3 points was included in the non-nutrition risk group. Pearson correlation analysis was used to explore the correlation between PMI and NRS 2002. Logistic regression was used to analyze the related factors of nutritional risk in SAP patients. Outcomes: There was no significant difference in baseline data between the two groups(P > 0.05). The levels of hemoglobin, albumin and prealbumin in the low PMI group were significantly lower than those in the normal PMI group, and the APACHE II score (7 d) and SOFA score (7 d) in the low PMI group were significantly higher than those in the normal PMI group (P < 0.05). The incidence of pancreatic infectious necrosis,pneumonia and multiple organ dysfunction in the low PMI group was higher than that in the normal PMI group, also the length of ICU stay in low PMI group was longer than that in the normal PMI group (P < 0.05). The Pearson correlation analysis showed a negative correlation between the PMI values and the nutritional risk score in SAP patients(r = -0.677,P = 0. 000). Multivariate logistic regression analysis showed that lower prealbumin and albumin level, higher APACHE II score (7d) and lower PMI were independent risk factors for nutritional risk in SAP patients. Conclusions: PMI has value in nutritional risk assessment andprognosis judgment of SAP patients.

参考文献/References:


[1] Garg PK, Singh VP. Organ Failure Due to Systemic Injury in Acute Pancreatitis. Gastroenterology, 2019, 156(7):2008-2023.
[2] 赵晓璠,唐 春,何 琴,等 . 高通量测序检测重症急性胰腺炎病人外周血细菌 DNA谱 . 肠外与肠内营养, 2021, 28(3):152-156.
[3] 李健雄,颜建建,高志强, 等 .重症急性胰腺炎的营养治疗 .宁夏医科大学学报, 2020, 42(1):100-104.
[4] 李 莉,宁华英,刘 晖, 等 .重症急性胰腺炎患者营养风险筛查与临床结局的相关性及价值探讨 . 重庆医学,2020,49(9):1413-1416.
[5] 尹 丹,黄云花 . 基于营养风险筛查 NRS2002系统的饮食干预在急性胰腺炎中的应用 . 护理实践与研究,2018,15(11):29-31.
[6] Arvanitakis M, Ockenga J, Bezmarevic M, et al. ESPEN guideline on clinical nutrition in acute and chronic pancreatitis.Clin Nutr, 2020,39(3):612-631.
[7] Masuda T, Shirabe K, Ikegami T, et al. Sarcopenia is a prognostic factor in living donor liver transplantation. Liver Transpl, 2014,20(4):401-407.
[8] Banks PA, Bollen TL, Dervenis C, et al. Classification of acute pancreatitis-2012: revision of the Atlanta classification and definitions by international consensus. Gut, 2013,62(1):102-111.
[9] Okamura H, Kimura N, Mieno M, et al. Preoperative sarcopenia is associated with late mortality after off-pump coronary artery bypass grafting. Eur J Cardiothorac Surg, 2020,58(1):121-129.
[10] Funamizu T, Nagatomo Y, Saji M, et al. Low muscle mass assessed by psoas muscle area is associated with clinical adverse events in elderly patients with heart failure. PLoS One, 2021, 16(2):e0247140.
[11] White JV, Guenter P, Jensen G, et al. Consensus statement: Academy of Nutrition and Dietetics and American Society for Parenteral and Enteral Nutrition:characteristics recommended for the identification and documentation of adult malnutrition (undernutrition). JPEN, 2012,36(3):275-283.
[12] 于 康,孙文彦 . 护理人员在营养风险筛查中的作用 . 中国护理管理,2020,20(3):324-327.
[13] Kondrup J, Rasmussen HH, Hamberg O, et al. Nutritional risk screening (NRS-2002): a new method based on an analysis of controlled clinical trials. Clin Nutr, 2003,22(2):321-326.
[14] 中华医学会 . 临床诊疗指南 . 肠外肠内营养学分册 . 人民卫生出版社, 2008.
[15] Cho JH, Kim TN, Chung HH, et al. Comparison of scoring systems in predicting the severity of acute pancreatitis. World J Gastroenterol,2015,21(8):2387-2394.
[16] 李秀川 .营养风险及急性生理学与慢性健康状况评分与危重症患者预后的关系 .中国实用护理杂志,2016,32(13):961-964.
[17] 曹 磊,瞿 萍,方传勤,等 . 急性缺血性脑卒中病人营养风险预测模型的建立和验证 . 肠外与肠内营养,2021,28(4):193-198.
[18] 许静涌,王 艳,唐普贤,等 . 华北和华中 11 家三甲医院小于 90 岁老年冠心病诊断相关组患者营养风险和营养不足发生率横断面调查及营养支持情况回顾性分析 . 中华临床营养杂志,2018,26(3):149-155.
[19] 张 敏,郭 放,付 莉, 等 .消化内科住院患者营养风险筛查及分析 .中华现代护理杂志,2013,19(8):902-904.
[20] Rivelsrud M, Paur I, Sygnestveit K, et al. Nutritional treatment is associated with longer survival in patients with pancreatic disease and concomitant risk of malnutrition. Clin Nutr, 2021,40(4):2128-2137.
[21] 朱 彬,邹聪聪,郑 昕 .终末期肝病的营养不良评价体系和营养支持治疗 .临床肝胆病杂志,2017,33(9):1699-1706.
[22] Kondrup J, Allison SP, Elia M, et al. ESPEN guidelines for nutrition screening 2002. Clin Nutr, 2003, 22:4151-4211.
[23] 何建冰,段红兵,康健乐,等 . 食管癌病人围手术期营养状况对其术后恢复的影响 . 肠外与肠内营养,2021,28(2):75-78.
[24] Woo HY, Oh SY, Lee H, et al. Evaluation of the association between decreased skeletal muscle mass and extubation failure after long-term mechanical ventilation. Clin Nutr, 2020, 39(9):2764-2770.
[25] 韩 芳,肖慧娟,张 翔, 等 .肝硬化及肝细胞癌患者腰肌横向厚度指数与营养风险的相关性分析 .临床肝胆病杂志,2020,36(8):1753-1756.
[26] 韦朝联 .L3骨骼肌质量指数对胃癌患者营养风险评估及预后影响的研究 .广西:广西医科大学,2015.

备注/Memo

备注/Memo:
基金项目 :安徽医科大学科研基金(2020xkj084) 作者简介 :邢桂枚,副主任护师,护理本科,主要从事外科护理工作。E-mail: 824673196@qq.com
更新日期/Last Update: 1900-01-01