[1]唐密密,杜 洁,罗 平,等.新型冠状病毒肺炎病人营养中添加谷氨酰胺双肽可行性分析[J].肠外与肠内营养杂志,2021,(01):55-59,64.[doi:DOI : 10.16151/j.1007-810x.2021.01.013]
 TANG Mi-mi,DU Jie,LUO Ping,et al.Feasibility of adding glutamine dipeptide to nutrition in patients with novel coronavirus pneumonia[J].PARENTERAL & ENTERAL NUTRITION,2021,(01):55-59,64.[doi:DOI : 10.16151/j.1007-810x.2021.01.013]
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新型冠状病毒肺炎病人营养中添加谷氨酰胺双肽可行性分析
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2021年01期
页码:
55-59,64
栏目:
综述
出版日期:
2021-01-10

文章信息/Info

Title:
Feasibility of adding glutamine dipeptide to nutrition in patients with novel coronavirus pneumonia
作者:
唐密密杜 洁罗 平梁宏岩龚志成刘 韶
中南大学湘雅医院药学部/中南大学医院药学研究所/湖南省临床药学研究中心,湖南长沙 410008
Author(s):
TANG Mi-mi DU Jie LUO Ping LIANG Hong-yan GONG Zhi-cheng LIU Shao
Department of Pharmacy, Xiangya Hospital, Central South University/The Hunan Institute of Pharmacy Practice and Clinical Research/Institute of Hospital Pharmacy, Central South University, Changsha 410008, Hunan, China
关键词:
新型冠状病毒 营养 谷氨酰胺
Keywords:
Novel coronavirus pneumonia Nutrition Glutamine
分类号:
R459.3,R563.1
DOI:
DOI : 10.16151/j.1007-810x.2021.01.013
文献标志码:
A
摘要:
研究新型冠状病毒肺炎(COVID-19)疫情中,对于感染 2019新型冠状病毒(SARS-CoV-2)的病人,是否应该在营养制剂中添加谷氨酰胺双肽。本文通过资料整理、文献回顾,综述了谷氨酰胺双肽的作用,探讨了其对COVID-19的潜在风险和临床获益。得出结论:①对于轻中症 COVID-19病人,可视病人免疫状态决定是否添加谷氨酰胺。②对于 COVID-19合并 ARDS的病人,若病情稳定且无肝肾功能衰竭,可考虑补充谷氨酰胺。③对于重症恢复期的病人,应考虑肠内补充谷氨酰胺。④对于儿科病人,目前尚缺乏明确谷氨酰胺补充使病人获益的证据,应谨慎使用。营养制剂中添加谷氨酰胺双肽对 COVID-19病人病情的影响需要进一步的临床研究。
Abstract:
There has been much concern about whether glutamine dipeptide should be added to nutrition for patients with novel coronavirus pneumonia (COVID-19). We reviewed the effects of glutamine dipeptide on COVID-19, and its potential risks or clinical benefits. For patients with mild to moderate COVID-19, glutamine can be added depending on the immune status. For patients with COVID-19 combined with ARDS, if the condition is stable and without liver or kidney failure, glutamine supplementation is recommended. For patients in convalescence, intestinal supplementation of glutamine is recommended. For pediatric patients, there is no clear evidence whether glutamine supplement benefits patients. Further studies are needed to figure out the effect of glutamine dipeptide on patients with COVID-19.

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备注/Memo

备注/Memo:
基金项目 :湖南省重点领域专项(NO.2020SK3022)湘财教指[2019]60号 作者简介 :唐密密,副研究员,医学博士,主要从事临床药学和人类营养学研究。E-mail:tangmimi1989@163.com 通讯作者 :龚志成,E-mail: gongzhicheng2013@163.com 共同通讯作者 :刘 韶,E-mail:liushao999@csu.edu.cn
更新日期/Last Update: 1900-01-01