[1]张力川,王玉洁,庄冰,等.三种营养不良诊断标准在头颈部恶性肿瘤放疗病人中的应用研究[J].肠外与肠内营养杂志,2021,(01):25-29.[doi:10.16151/j.1007-810x.2021.01.006]
 ZHANG Li-chuan,WANG Yu-jie,ZHUANG Bing,et al.Application of three diagnostic criteria of malnutrition in patients with head and neck cancer during radiotherapy[J].PARENTERAL & ENTERAL NUTRITION,2021,(01):25-29.[doi:10.16151/j.1007-810x.2021.01.006]
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三种营养不良诊断标准在头颈部恶性肿瘤放疗病人中的应用研究
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2021年01期
页码:
25-29
栏目:
论著
出版日期:
2021-01-10

文章信息/Info

Title:
Application of three diagnostic criteria of malnutrition in patients with head and neck cancer during radiotherapy
作者:
张力川王玉洁庄冰 张彤金三丽曹怡纬李红梅龚丽青王艳莉方玉肖绍文郑宝敏孙艳路潜
1.北京大学护理学院内外科护理学教研室,北京 100191;2.山西省中西医结合医院胸普外科,山西太原 030013;3.北京大学肿瘤医院暨北京市肿瘤防治研究所营养科,北京 100142;4.北京 大学肿瘤医院暨北京市肿瘤防治研究所放射治疗科 恶性肿瘤发病机制及转化研究教育部重点实验室,北京 100142
Author(s):
ZHANG Li-chuan WANG Yu-jie ZHUANG Bing ZHANG Tong JIN San-li CAO Yi-wei LI Hong-mei GONG Li-qing WANG Yan-li FANG Yu XIAO Shao-wen ZHENG Bao-minSUN Yan LU Qian
1. Division of Medical and Surgical Nursing, Peking University School of Nursing, Beijing 100191, China;2. Division of Surgical Nursing, Shanxi Hospital of Integrated Traditional and Western Medicine , Taiyuan 030013, Shanxi, China;3.Division of Clinical Nutrition,Peking University Cancer Hospital & Institute, Beijing 100142, China;4. Key laboratory of Carcinogenesis and Translational Research, Ministry of Education, Department of Radiation Oncology, Peking University Cancer Hospital & Institute, Beijing 100142,China
关键词:
头颈部恶性肿瘤 放疗 营养不良 GLIM
Keywords:
Head and Neck Cancer Radiotherapy Malnutrition GLIM Criteria
分类号:
R459.3,R739.91
DOI:
10.16151/j.1007-810x.2021.01.006
文献标志码:
A
摘要:
目的:采用不同营养不良评定标准,描述并比较头颈部恶性肿瘤病人在放疗期间营养不良的变化情况。 方法:在北京大学肿瘤医院放疗科选取拟接受放疗的头颈部恶性肿瘤病人,分别在放疗前、放疗中期和放疗结束时随访。采用营养不良评定标准全球领导人共识(GLIM)标准、欧洲肠外肠内营养学会2015年营养不良专家共识(ESPEN 2015)和病人参与主观全面评定(PG-SGA)进行营养评定,其中,营养筛查采用营养风险筛查2002,肌肉量评价采用生物电阻抗分析法测得的四肢骨骼肌指数和去脂体质指数。 结果:共纳入502名头颈部恶性肿瘤病人。随着放疗进行,营养风险的比例显著增加;三种标准诊断的营养不良比例均显著增加;且三种标准得到的结果一致性均较差(0.303 ≤ Kappa ≤ 0.681)。 结论:头颈部恶性肿瘤病人在放疗期间的营养风险和营养不良比例均显著增加,不同营养不良诊断标准得出的结果差异明显。建议结合临床结局指标进行评价研究,使其更具临床意义。
Abstract:
Objective: To describe and compare the prevalence of malnutrition in patients with head and neck cancer(HNC)during radiotherapy by using different diagnostic criteria. Methods: Patients with HNC who planned to receive radiotherapy were recruited from the radiotherapy department of Peking University Cancer Hospital. Data were collected at three-time points: before, during, and after treatment. Global Leadership Initiative on Malnutrition (GLIM criteria), European Society of Clinical Nutrition and Metabolism consensus 2015 (ESPEN 2015 criteria), and patient generated subjective global assessment (PG-SGA) were used for nutritional assessment. Nutritional risk screening 2002 was used for nutritional screening. The body composition was tested with bioelectrical impedance analysis. Appendicular skeletal muscle index and fat-free mass index were used for evaluating reduced muscle mass. Results: 502 HNC patients were enrolled. With the progress of radiotherapy, the proportion of nutritional risk increased significantly; the proportion of malnutrition diagnosed by the three criteria increased significantly; and the consistency of the results obtained by the three criteria was poor (0.303 ≤ Kappa ≤ 0.681). Conclusion: The nutritional risk and malnutrition ratio of patients with HNC during radiotherapy were significantly increased, and the results obtained by different malnutrition diagnostic criteria were significantly different. It is recommended that the evaluation study should be combined with clinical outcome index to make it more clinically significance.

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备注/Memo

备注/Memo:
作者简介 :张力川,护理博士研究生,主要从事肿瘤护理和临床营养研究。E-mail:zhanglichuan@bjmu.edu.cn 通讯作者 :路 潜,E-mail:luqian@bjmu.edu.cn 共同通讯作者 :孙 艳,E-mail:sunemail@yahoo.com
更新日期/Last Update: 1900-01-01