[1]陈 维,杨达宇,孙景存,等.肠外营养个体化治疗在具有营养风险的晚期肺癌病人中的临床意义[J].肠外与肠内营养杂志,2020,(06):355-357.[doi:DOI : 10.16151/j.1007-810x.2020.06.008]
　CHEN Wei,YANG Da-yu,SUN Jing-cun,et al.Clinical significance of individualized parenteral nutrition therapy in patients with advanced lung cancer and nutritional risk[J].PARENTERAL & ENTERAL NUTRITION,2020,(06):355-357.[doi:DOI : 10.16151/j.1007-810x.2020.06.008]
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肠外营养个体化治疗在具有营养风险的晚期肺癌病人中的临床意义
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2020年06期
页码:
355-357
栏目:
论著
出版日期:
2020-11-10

文章信息/Info

Title:
Clinical significance of individualized parenteral nutrition therapy in patients with advanced lung cancer and nutritional risk
作者:
陈 维; 杨达宇; 孙景存; 张学敏
河北省沧州中西医结合医院肺病科，河北沧州 061000
Author(s):
CHEN Wei;  YANG Da-yu;  SUN Jing-cun;  ZHANG Xue-min
Department of Respiratory, Cangzhou Hospital of Integrated Traditional and Western Medicine of Hebei Province,Cangzhou 061000, Hebei, China
关键词:
肠外营养 ; 个体化治疗 ; 晚期肺癌
Keywords:
Parenteral nutrition;  Individualized treatment;  Advanced lung cancer
分类号:
R734.2
DOI:
DOI : 10.16151/j.1007-810x.2020.06.008
文献标志码:
A
摘要:
目的：评价肠外营养（PN）个体化治疗对具有营养风险的晚期肺癌病人营养状况、免疫功能及生活质量的影响。 方法：110例具有营养风险的晚期肺癌病人随机分为个体化 PN组和对照组。两组均接受 PN支持治疗，个体化 PN组由临床药师开具个体化 PN处方进行 PN，对照组给予工业化生产的三腔袋进行 PN。比较两组治疗前及治疗 3周后血清白蛋白、前白蛋白、T淋巴细胞亚群的变化、体质量指数（BMI）和生活质量评分（QOL评分）。结果：治疗 3周后，个体化 PN组血清白蛋白、前白蛋白、CD4+、CD8+、CD4+/CD8+、BMI和 QOL评分均较治疗前和对照组升高（P < 0.05）。 结论：PN个体化治疗可改善具有营养风险的晚期肺癌病人的免疫功能和生活质量。
Abstract:
Objective: To evaluate the effect of individualized parenteral nutrition (PN) therapy on nutritional status, immune function and quality of life (QOL) in patients with advanced lung cancer and nutritional risk. Methods: A total of 110 patients with nutritional risk of advanced lung cancer were randomly divided into individualized parenteral nutrition group and control group. The patients of the two groups received PN support therapy. Patients in the individualized parenteral nutrition group were given PN prescribed by clinical pharmacists, while patients in the control group were given PN by industrial production of three-chamber bags. The levels of serum albumin, prealbumin, Tlymphocyte subsets before and 3 weeks after PN therapy were compared between two groups. The body mass index(BMI) and QOL score were evaluated and compared as well. Results: After 3 weeks of PN treatment, the levels of serum albumin, prealbumin, CD4+ , CD8+ , CD4+/CD8+ , BMI and QOL scores were all increased in the individualized parenteral nutrition group compared with those before PN treatment and those in the control group(P < 0.05). Conclusion: The individualized PN therapy can improve immune function and QOL in patients with advanced lung cancer and at nutritional risk.

参考文献/References:


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备注/Memo

备注/Memo:
作者简介 ：陈 维，主治医师，医学硕士，从事呼吸疾病的治疗和临床研究工作。E-mail:cw-china-good@163.com
更新日期/Last Update: 1900-01-01