[1]李春蕾,董凤齐,董 杰,等.患者主观整体评估在肝癌肝切除术后并发症中的预测作用[J].肠外与肠内营养杂志,2020,(05):274-279.[doi:10.16151/j.1007-810x.2020.04.005]
　LI Chun-lei,Dong Feng-qi,DONG Jie,et al.Predictive power of PG-SGA for post-hepatectomy complications in liver cancer patients[J].PARENTERAL & ENTERAL NUTRITION,2020,(05):274-279.[doi:10.16151/j.1007-810x.2020.04.005]
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患者主观整体评估在肝癌肝切除术后并发症中的预测作用
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2020年05期
页码:
274-279
栏目:
论著
出版日期:
2020-09-10

文章信息/Info

Title:
Predictive power of PG-SGA for post-hepatectomy complications in liver cancer patients
作者:
李春蕾 1; 董凤齐 2; 董 杰 1; 曾亚奇1; 王 昆 1; 宋天强 2
1.天津医科大学肿瘤医院营养科/国家肿瘤临床医学研究中心/天津市肿瘤防治重点实验室/天津市恶性肿瘤临床医学研究中心；2.天津医科大学肿瘤医院肝胆肿瘤科/肝癌防治研究中心，天津 300060
Author(s):
LI Chun-lei1;  Dong Feng-qi2;  DONG Jie1;  ZENG Ya-qi1;  WANG Kun1;  SONG Tian-qiang1
1.Department of Nutrition, Tianjin Medical University Cancer Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer；2. Department of Hepatobiliary Oncology, Tianjin Medical University Cancer Hospital, Liver Cancer Centre, Tianjin 300060, China
关键词:
肝切除术 ; 原发性肝癌 ; 术后并发症 ; 营养评估 ; PG-SGA
Keywords:
Primary liver cancer;  Hepatectomy;  Postoperative complications;  Nutrition assessment;  PG-SGA
分类号:
R735.7;R153.9
DOI:
10.16151/j.1007-810x.2020.04.005
文献标志码:
A
摘要:
目的：评估患者主观整体评估（PG-SGA）对肝癌肝切除术后并发症的预测价值。 方法：本研究是一项前瞻性队列研究，共纳入肝癌肝切除病人200例，使用PG-SGA对其进行营养评估。使用Clavien-Dindo分级评估术后并发症发生情况，采用Logistic回归分析确定术后并发症发生的危险因素。 结果：根据PG-SGA评估结果，轻中度营养不良发生率43.5%，重度营养不良的发生率为11%。II级及以上并发症发生率是25.5%，其中重度营养不良病人（PG-SGA ≥ 9 分）并发症发生率为 45.45%。多因素 Logistic 分析结果显示，手术方式（开腹）[OR = 4.00;95%CI：1.28 ~ 12.44]、失血量（≥200 mL）(OR = 3.68, 95%CI：1.83 ~ 7.39)和 PG-SGA ≥ 9(OR = 2.80, 95%CI: 1.05 ~7.46)是术后并发症发生的独立风险因素(P < 0.05)。 结论：术前重度营养不良是术后并发症发生的风险因素，应在术前给与合适的营养治疗和临床防范措施以促进术后恢复。
Abstract:
Objective: The aim of the study was to determine the predictive value of Patient-Generated Subjective Global Assessment (PG-SGA) for complications after hepatectomy in patients with liver cancer. Methods: A total of 200 patients with liver cancer who underwent hepatectomy were enrolled. Nutritional evaluation was performed using PG-SGA. Clinical data and details of surgery were retrospectively analyzed. Logistic regression analysis was used to determine the risk factors for postoperative complications. Results: According to the PG-SGA, the incidence of mild to moderate malnutrition was 43.5%, and the severe malnutrition was 11%. The incidence of Grade II and above postoperative complications was 25.5% in the overall and the complication rate of severely malnourished patients (PG SGA ≥ 9 points) was 45.45%. The results of multivariate Logistic analysis showed that laparotomy [OR = 4; 95% CI: 1.28 ~ 12.44], blood loss (≥ 200 mL) (OR = 3.68, 95%CI: 1.83 ~ 7.39) and PG-SGA ≥ 9 (OR = 2.80, 95%CI:1.05 ~ 7.46) were independent risk factors for postoperative complications in patient with liver cancer. Conclusion: Severe malnutrition was found to be a risk factor for postoperative complications. Appropriate nutritional treatment and clinical precautions should be given before surgery to promote postoperative recovery.

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备注/Memo

备注/Memo:
作者简介 ：李春蕾，营养医师，医学硕士，从事肿瘤临床营养专业。E-mail: lcltjmu507@163.com 通讯作者 ：宋天强，E-mail: tjchi@hotmail.com
更新日期/Last Update: 1900-01-01