[1]魏 萌,吴允孚.再喂养综合征的研究进展[J].肠外与肠内营养杂志,2020,(04):243-247.[doi:DOI : 10.16151/j.1007-810x.2020.04.012]
　WEI Meng,WU Yun-fu.Research Progress of Refeeding Syndrome[J].PARENTERAL & ENTERAL NUTRITION,2020,(04):243-247.[doi:DOI : 10.16151/j.1007-810x.2020.04.012]
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再喂养综合征的研究进展
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2020年04期
页码:
243-247
栏目:
综述
出版日期:
2020-07-10

文章信息/Info

Title:
Research Progress of Refeeding Syndrome
作者:
魏 萌; 吴允孚
南京医科大学附属苏州医院重症医学科，江苏苏州 215001
Author(s):
WEI Meng;  WU Yun-fu
Department of Intensive Care Unit, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou 215001, Jiangsu, China
关键词:
再喂养综合征 ; 营养不良 ; 微营养素 ; 肠内营养 ; 肠外营养
Keywords:
Refeeding syndrome;  Malnutrition;  Micronutrients;  Enteral nutrition;  Parenteral nutrition
分类号:
R459.3
DOI:
DOI : 10.16151/j.1007-810x.2020.04.012
文献标志码:
A
摘要:
再喂养综合征（RFS）是指严重营养不良或禁食病人在重新接受能量供给后发生的水、电解质平衡紊乱及由此产生的一系列代谢变化。其主要特征是电解质紊乱（尤其是低磷血症）、维生素 B1缺乏、水钠潴留等，最终导致心力衰竭、呼吸衰竭等严重并发症。由于缺乏特征性临床表现，RFS易被临床医生所忽视，因此早期识别高危病人并实施干预可减少 RFS的发生。目前对于 RFS的治疗主要包括补充电解质及维生素、纠正体液失衡和限制热量 摄入，同时持续监测血清电解质水平及生命体征变化。本文对 RFS的近期研究进展进行综述，以提高临床医师对RFS的认识，进一步优化对 RFS病人的诊断及治疗。
Abstract:
Refeeding syndrome (RFS) is a series of metabolic disorders manifesting with fluid and electrolyte imbalances, which occurs in malnourished or fasting patients after reinstitution of nutrition. The main characteristics of RFS are electrolyte disturbances (especially hypophosphatemia), thiamine deficiency, sodium-fluid retention and so on, finally resulting in severe complications such as cardiac failure and respiratory failure. Due to the lack of specific clinical manifestations, the diagnosis of RFS tends to fail. Therefore, early identification and intervention of patients who are at high risk could reduce the occurrence of RFS. So far, the treatment of RFS mainly includes repletion of electrolytes and thiamine, correction of fluid imbalances and caloric restriction, along with continuous monitoring of changes of serum electrolyte levels and vital signs. This review provides an overview of current research progress on RFS in order to deepen understanding of RFS and further optimize the diagnosis and treatment for clinicians.

参考文献/References:


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备注/Memo

备注/Memo:
基金项目 ：苏州市临床重点病种诊疗技术专项项目（LCZX201607） 作者简介 ：魏 萌，医学硕士研究生，从事危重症营养的相关研究。E-mail：icuwei@126.com 通讯作者 ：吴允孚，E-mail：icuwu@163.com
更新日期/Last Update: 1900-01-01