参考文献/References:
[1] Dyerberg J, Bang HO. Haemostatic function and platelet polyunsaturated fatty acids in Eskimos. Lancet, 1979, 2(8140):433-435.
[2] Atlantis E, Cochrane B. The association of dietary intake and supplementation of specific polyunsaturated fatty acids with
inflammation and functional capacity in chronic obstructive pulmonary disease: a systematic review. Int J Evid Based Healthc, 2016, 14(2):53-63.
[3] Williams NC, Hunter KA, Shaw DE, et al. Comparable reductions in hyperpnoea-induced bronchoconstriction and markers of airway inflammation after supplementation with 6·2
and 3·1 g/d of long-chain n-3 PUFA in adults with asthma. Br J Nutr, 2017, 117(10):1379-1389.
[4] Gioxari A, Kaliora AC, Marantidou F, et al. Intake of ω -3 polyunsaturated fatty acids in patients with rheumatoid arthritis: A systematic review and meta-analysis. Nutrition, 2018, 45(6):114-124.
[5] Serhan CN. Pro-resolving lipid mediators are leads for resolution physiology. Nature, 2014, 510(7503):92-101.
[6] Barnig C, Frossard N, Levy BD. Towards targeting resolution pathways of airway inflammation in asthma. Pharmacol Ther, 2018, 186(1): 98-113.
[7] Miyata J, Arita M. Role of omega-3 fatty acids and their metabolites in asthma and allergic diseases. Allergol Int, 2015, 64 (1):27-34.
[8] Chiang N, Serhan CN. Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors. Mol Aspects Med, 2017, 58(3): 114-129.
[9] Kasuga K, Yang R, Porter TF, et al. Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. J Immunol, 2008, 181(12):8677-8687.
[10] Lambrecht BN, Hammad H. The immunology of asthma.Nat Immunol, 2015, 16(1):45-56.
[11] Bell MC, Busse WW. Severe asthma: an expanding and mounting clinical challenge. J Allergy Clin Immunol Pract, 2013, 1(2):110-121.
[12] Laidlaw TM, Boyce JA. Cysteinyl leukotriene receptors, old and new; implications for asthma. Clin Exp Allergy, 2012, 42(9):1313-1320.
[13] 中华医学会呼吸病学分会哮喘学组 . 支气管哮喘防治指南(2016年版).中华结核和呼吸杂志,2016,(9):675-697.
[14] B?ck M. Omega-3 fatty acids in atherosclerosis and coronary artery disease. Future Sci OA, 2017, 3(4), FSO236.
[15] 汪 灏，李秋荣，马 健，等．二十二碳六烯酸对人树突状细胞基因表达谱的影响．肠外与肠内营养，2005，12(2)：67-69．
[16] Chiurchiù V, Leuti A, Dalli J, et al. Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses. Sci Transl Med, 2016,8(353):353ra111.
[17] Li Y, Dalli J, Chiang N, et al. Plasticity of leukocytic exudates in resolving acute inflammation is regulated by MicroRNA and proresolving mediators. Immunity, 2013, 39(5):885-898.
[18] Dalli J, Winkler JW, Colas RA, et al. Resolvin D3 and aspirintriggered resolvin D3 are potent immunoresolvents. Chem Biol, 2013, 20(2):188-201.
[19] Chiang N, Fredman G, B?ckhed F, et al. Infection regulates proresolving mediators that lower antibiotic requirements. Nature, 2012, 484(7395):524-528.
[20] Chiang N, Dalli J, Colas RA, et al. Identification of resolvin D2 receptor mediating resolution of infections and organ protection. J Exp Med, 2015, 212(8):1203-1217.
[21] Arita M, Ohira T, Sun YP, et al. Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation. J Immunol, 2007, 178(6):3912-3917.
[22] Ohira T, Arita M, Omori K, et al. Resolvin E1 receptor activation signals phosphorylation and phagocytosis. J Biol Chem, 2010,285(5):3451-3461.
[23] Freire MO, Dalli J, Serhan CN, et al. Neutrophil Resolvin E1 Re‐ceptor Expression and Function in Type 2 Diabetes. J Immunol, 2017,198(2):718-728.
[24] Kim N, Ramon S, Thatcher TH, et al. Specialized proresolving mediators (SPMs) inhibit human B-cell IgE production. Eur J Immunol, 2016, 46(1):81-91.
[25] Aoki H, Hisada T, Ishizuka T, et al. Protective effect of resolvin E1 on the development of asthmatic airway inflammation. Biochem Biophys Res Commun, 2010, 400(1):128-133.
[26] Zambalde ?P, Teixeira MM, Favarin DC, et al. The antiinflammatory and pro-resolution effects of aspirin-triggered RvD1 (AT-RvD1) on peripheral blood mononuclear cells from patients with severe asthma. Int Immunopharmacol, 2016, 35(3):142-148.
[27] Levy BD, Kohli P, Gotlinger K, et al. Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness. J Immunol, 2007, 178(1):496-502.
[28] Krishnamoorthy N, Burkett PR, Dalli J, et al. Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation. J Immunol, 2015, 194(3):863-867.
[29] Mickleborough TD, Lindley MR, Ionescu AA, et al. Protective effect of fish oil supplementation on exercise-induced bronchoconstriction in asthma. Chest, 2006, 129(1):39-49.
[30] Li J, Xun P, Zamora D,et al.Intakes of long-chain omega-3 (n-3) PUFAs and fish in relation to incidence of asthma among American young adults: the CARDIA study. Am J Clin Nutr,2013, 97(1):173-178.
[31] Burns JS, Dockery DW, Neas LM, et al. Low dietary nutrient intakes and respiratory health in adolescents. Chest, 2007, 132(1):238-245.
[32] De Caterina R, Liao JK, Libby P. Fatty acid modulation of endo‐thelial activation. Am J Clin Nutr, 2000, 71(1 Suppl):213S-23S.
[33] Bisgaard H, StokholmJ, Chawes BL, et al. Fish oil-derived fatty acids in pregnancy and wheeze andasthma in offspring. N Engl J Med, 2016, 375(26):2530-2539.
[34] Hansen S, Str?m M, Maslova E, et al. Fish oil supplementation during pregnancy and allergic respiratory disease in the adult offspring. J Allergy Clin Immunol, 2017, 139(1):104-111.
[35] Muley P, Shah M, Muley A. Omega-3 Fatty Acids Supplementa‐tion in Children to Prevent Asthma: Is It Worthy ? - A Systematic Review and Meta-Analysis. J Allergy(Cairo), 2015,2015: 312052.