[1]作者简介 ：朱菊训,主管护师,医学硕士,等.胰岛素泵治疗在脑卒中合糖尿病病人肠内营养实施中的应用评价[J].肠外与肠内营养杂志,2019,(04):223-227.[doi:DOI : 10.16151/j.1007-810x.2019.04.007]
　ZHU Ju-xun,LIU Ling,YAN Jin-ling,et al.Evaluation of the efficiency of continuous insulin infusion in the administration enteral nutrition in stroke patients complicated with diabetes[J].PARENTERAL & ENTERAL NUTRITION,2019,(04):223-227.[doi:DOI : 10.16151/j.1007-810x.2019.04.007]
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胰岛素泵治疗在脑卒中合糖尿病病人肠内营养实施中的应用评价
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2019年04期
页码:
223-227
栏目:
论著
出版日期:
2019-07-10

文章信息/Info

Title:
Evaluation of the efficiency of continuous insulin infusion in the administration enteral nutrition in stroke patients complicated with diabetes
作者:
作者简介 ：朱菊训; 主管护师; 医学硕士; 从事神经内科专业。E-mail：zhujuxun@sdhospital.com 通讯作者 ：刘 玲; E-mail：liuling@sdhospital.com
山东第一医科大学第一附属医院神经内科 山东省千佛山医院，山东济南250014
Author(s):
ZHU Ju-xun;  LIU Ling;  YAN Jin-ling;  DU Lin-lin;  SUN Ying-ying;  ZHANG Ning-ning
Department of Neurology，Shandong Provincial Qianfoshan Hospital,the First Hospital Affiliated with Shandong First Medical University, Jinan 250014, Shandong,China
关键词:
肠内营养 ; 血糖控制 ; 营养状态 ; 胰岛素泵 ; 并发症
Keywords:
Enteral nutrition;  Glucose control;  Nutritional status;  Insulin pump;  Complications
分类号:
R459.3
DOI:
DOI : 10.16151/j.1007-810x.2019.04.007
文献标志码:
A
摘要:
目的：观察不同的胰岛素使用方式对持续肠内营养(EN) 输注的脑卒中合并糖尿病病人的血糖、营养状态及输注并发症的影响。 方法：选取脑卒中合并糖尿病持续 EN输注病人 160例，采用便利抽样法将入选病人随机分为观察组 79例、对照组各 81例，观察组采用胰岛素持续皮下泵入的方式控制血糖，对照组采用胰岛素分次皮下注射的方式控制血糖。观察两组病人日常血糖水平、营养状态、高血糖、低血糖发生率及病人 EN并发症情况。 结果：两组病人的空腹血糖、喂养开始 2 h、喂养结束时、喂养结束后 2 h血糖比较均有统计学意义(P < 0.05）；两组病人高血糖、低血糖发生率比较均有统计学意义(P < 0.05）；两组病人 EN并发症情况比较有统计学意义(P < 0.05）；两组病人白蛋白、前蛋白比较均有统计学意义(P < 0.05）。 结论：脑卒中合并糖尿病持续 EN输注病人，采用胰岛素持续皮下泵入的方式控制血糖，有利于病人的血糖达标及稳定，营养状态改善，减少 EN并发症的发生，提高治疗有效率。
Abstract:
Objective: To observe the effects of different insulin administration patterns on blood glucose, nutritional status and infusion associated complications in stroke patients complicated with diabetes treated with enteral nutrition (EN). Methods: 160 stroke patients with diabetes sustained by enteral nutrition infusion were included. The patients were randomly divided into the intervention group (79 cases) and the control group (81 cases) using convenient sampling method. Patients in the intervention group were given continuous subcutaneous insulin pump to control blood glucose, while the control group used separate subcutaneous insulin injection. The daily blood glucose level, nutritional status, incidence of hyperglycemia and hypoglycemia and enteral nutrition associated complications of the both groups were observed. Results: The fasting blood glucose levels, as well as blood glucose levels at 2h after feeding initiation, at the end of feeding and 2h after the end of feeding between the two groups was statistically significant (P < 0.05). The incidence of hyperglycemia and hypoglycemia in the two groups was statistically significant (P < 0.05). In addition, there was a statistically significant difference in incidence of enteral nutrition associated complications, as well as the levels of albumin and pre-albumin between the two groups (P < 0.05). Conclusion: In stroke patients complicated with diabetes, continuous subcutaneous insulin infusion, in comparison to separate insulin injection, showed great effects in maintaining blood glucose, improving nutritional status, reducing the incidence of enteral nutrition associated complications and optimizing clinical outcomes.

参考文献/References:


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备注/Memo

备注/Memo:
作者简介 ：朱菊训，主管护师，医学硕士，从事神经内科专业。E-mail：zhujuxun@sdhospital.com 通讯作者 ：刘 玲，E-mail：liuling@sdhospital.com
更新日期/Last Update: 1900-01-01