[1]廖婵婵,徐海霞,张红萍.体成分分析指导膳食结构调整对妊娠期糖尿病病人血糖、血脂、体质量增长和妊娠结局的影响[J].肠外与肠内营养杂志,2025,(01):42-47.[doi:10.16151/j.1007-810x.2025.01.007]
 LIAO Chan-chan,XU Hai-xia,ZHANG Hong-ping.Effects of dietary adjustment guided by body composition analysis on blood glucose, blood lipids, weight gain and pregnancy outcome in patients with gestational diabetes[J].PARENTERAL & ENTERAL NUTRITION,2025,(01):42-47.[doi:10.16151/j.1007-810x.2025.01.007]
点击复制

体成分分析指导膳食结构调整对妊娠期糖尿病病人血糖、血脂、体质量增长和妊娠结局的影响()
分享到:

《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2025年01期
页码:
42-47
栏目:
论著
出版日期:
2025-04-02

文章信息/Info

Title:
Effects of dietary adjustment guided by body composition analysis on blood glucose, blood lipids, weight gain and pregnancy outcome in patients with gestational diabetes
作者:
廖婵婵徐海霞张红萍
温州市人民医院/温州市妇幼保健院/温州医科大学温州市第三临床学院 妇产科,浙江温州 325000
Author(s):
LIAO Chan-chan XU Hai-xia ZHANG Hong-ping
Obstetrics and Gynecology, Wenzhou People’s Hospital/Wenzhou Women’s and Children’s Hospital/Wenzhou Third Clinical College of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China
关键词:
妊娠期糖尿病 体成分分析 膳食结构调整 血糖 血脂 体质量增长 妊娠结局
Keywords:
Gestational diabetes mellitus Body composition analysis Dietary structure adjustmen Blood glucose Blood lipids Weight gain Pregnancy outcome
分类号:
R714.25,R459.3
DOI:
10.16151/j.1007-810x.2025.01.007
文献标志码:
A
摘要:
目的:评价体成分分析指导膳食结构调整对妊娠期糖尿病(GDM)病人血糖、血脂、体质量增长和妊娠结局的影响。 方法:选入2021年5月 ~ 2023年10月在温州市人民医院定期产前检查并分娩的GDM病人122例作为研究对象,随机分为A组和B组,各61例。A组予以GDM常规营养干预,B组在A组基础上依据体成分分析进行膳食结构调整。另选择同期50例正常孕妇作为对照组。对比三组血糖、血脂、体质量增长和妊娠结局。 结果:干预后,三组FPG、2hPG水平显著降低,TC、TG和LDL-C水平显著升高;A组和B组HbA1c水平显著降低,对照组HDL-C水平显著升高(P < 0.05)。A组干预后FPG、2hPG、HbA1c、TC、TG、LDL-C水平显著高于B组和对照组(P < 0.05)。B组干预后FPG、TC、LDL-C水平显著高于对照组(P < 0.05)。A组和B组分娩前体质量、孕期增加体质量均显著大于对照组,B组显著小于A组(P < 0.05)。对照组和B组孕期体质量增加达标率比较无显著差异(P >0.05),但均显著高于A组(P < 0.05)。对照组和B组剖宫产率、妊娠期并发症及围生儿不良结局总发生率比较无显著差异(P > 0.05),但均显著低于A组(P < 0.05)。 结论:体成分分析指导膳食结构调整有助于控制GDM病人的血糖水平,维持孕期体质量合理增长,降低剖宫产率,减少妊娠并发症及围生儿不良结局的发生风险。
Abstract:
Objective: To evaluate the effect of dietary adjustment guided by body composition analysis on blood glucose, , blood lipids, weight gain and pregnancy outcome in patients with gestational diabetes mellitus (GDM). Methods: A total of 122 GDM patients who had regular prenatal check-ups and gave birth at Wenzhou People’s Hospital from May 2021 to October 2023 were selected as the research subjects and were randomly divided into Group A and Group B, with 61 cases in each group. Group A was given routine nutritional intervention with GDM, and Group B was adjusted their dietary structure based on body composition analysis. Another 50 normal pregnant women were selected as the control group. Three groups were compared for blood glucose, lipids, and body mass growth and pregnancy outcomes. Results: After intervention, the levels of FPG and 2hPG in the three groups were significantly decreased, while the levels of TC, TG, and LDL-C were significantly increased; The HbA1c levels in Group A and Group B were decreased significantly, while the HDL-C levels in the control group were significantly increased (P < 0.05). After intervention, the levels of FPG, 2hPG, HbA1c, TC, TG, and LDL-C in Group A were significantly higher than those in Group B and the control group (P < 0.05). After intervention, the levels of FPG, TC, and LDL-C in group B were significantly higher than those in the control group (P < 0.05). The predelivery body mass and increased body mass during pregnancy in Group A and Group B were significantly higher than those in the control group, while Group B was significantly lower than Group A (P < 0.05). There was no significant difference in the compliance rate of body mass increase during pregnancy between the control group and group B (P > 0.05), but both groups were significantly higher than group A (P < 0.05). There was no significant difference in the cesarean section rate, pregnancy complications, and overall incidence of adverse perinatal outcomes between the control group and group B (P > 0.05), but they were significantly lower than group A (P < 0.05). Conclusion: Dietary structure adjustment guided body composition analysis can help to control blood glucose levels in GDM patients, maintain reasonable weight gain during pregnancy, reduce cesarean section rates, and reduce the risk of pregnancy complications and adverse perinatal outcomes.

参考文献/References:


[1] 岳晓玲, 战 芳, 韩 璐. 大连地区妊娠期糖尿病孕妇妊娠中期维生素A、E水平研究[J]. 肠外与肠内营养, 2019, 26(2): 70-73.
[2] Sert UY, Ozgu-Erdinc AS. Gestational diabetes mellitus screening and diagnosis[J]. Adv Exp Med Biol, 2021, 1307: 231-255.
[3] Ye WR, Luo C, Huang J, et al. Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and metaanalysis[J]. BMJ, 2022, 377: e067946.
[4] Moon JH, Jang HC. Gestational diabetes mellitus: diagnostic approaches and maternal-offspring complications[J]. DiabetesMetab J, 2022, 46(1): 3-14.
[5] 吴晓婧, 罗 琼. 妊娠期糖尿病子代近远期健康影响及机制研究进展[J]. 实用妇产科杂志, 2024, 40(1): 9-14.
[6] Gao Y, Zhou M, Xu X, et al. Body composition and risk of gestational diabetes mellitus: a univariable and multivariablemendelian randomization study[J]. J Diabetes Investig, 2024, 15(3): 346-354.
[7] 中国营养学会. 中国居民膳食营养素参考摄入量[J]. 营养学报,2001, 23(3): 193-196.
[8] 丰 暖, 史志平, 刘晓宁, 等. 妊娠早期营养指标与新生儿出生体质量的相关性研究[J]. 肠外与肠内营养, 2023, 30(3): 144-147, 153.
[9] 段 成, 齐晓玲, 徐礼五, 等. 胰岛素强化治疗不同类型妊娠糖尿病患者的临床研究[J]. 中国妇产科临床杂志, 2020, 21(3): 281-282.
[10] Bedell S, Hutson J, de Vrijer B, et al. Effects of maternal obesity and gestational diabetes mellitus on the placenta: currentknowledge and targets for therapeutic interventions[J]. Curr Vasc Pharmacol, 2021, 19(2): 176-192.
[11] Sweeting A, Wong J, Murphy HR, et al. A clinical update on gestational diabetes mellitus[J]. Endocr Rev, 2022, 43(5):763-793.
[12] Holmes CJ, Racette SB. The utility of body composition assessment in nutrition and clinical practice: an overview of current methodology[J]. Nutrients, 2021, 13(8): 2493.
[13] 吴 燕, 朱燕飞, 吕美丹, 等. 妊娠期糖尿病患者孕期体成分分析[J]. 中国妇幼保健, 2021, 36(4): 748-750.
[14] 黄少华, 彭 磊, 杜 岩, 等. 徐州地区妊娠糖尿病孕妇体质量及 体 成 分 对 妊 娠 结 局 的 影 响 [J]. 营 养 学 报 , 2020, 42(1):102-104.
[15] Karaflou M, Goulis DG. Body composition analysis: a snapshot across the perimenopause[J]. Maturitas, 2024, 180: 107898.
[16] 董冠楠, 王 恺, 杨玉鹏, 等. 人体成分分析仪在维持性血液透析患者营养评估中的应用[J]. 医学临床研究, 2020, 37(6): 824-826, 830.
[17] 刘莉莉, 谭容容, 陶新城, 等. 孕期体脂率和甘油三酯水平与妊娠期糖尿病的关系[J]. 中国计划生育学杂志, 2023, 31(4): 813-817, 995.
[18] 张立军, 钟利若, 梁训宏. 正常妊娠妇女、妊娠期高血压及妊娠期糖尿病患者脂类、载脂蛋白、血浆蛋白代谢变化的探讨[J]. 临床和实验医学杂志, 2016, 15(8): 786-788.
[19] 王新玲, 冯 静, 李 丽, 等. 人体成分分析仪指导营养治疗对妊娠期糖尿病的影响[J]. 中国现代医学杂志, 2019, 29(13):64-67.

备注/Memo

备注/Memo:
基金项目 :温州市科研项目(重大,项目编号ZY2021025);基础性公益科研项目(项目编号Y20210328)通讯作者 :张红萍,E-mail:xiaocanglan014@163.com
更新日期/Last Update: 1900-01-01