[1]陈爱民,王 磊,高 雅,等.老年营养风险指数在老年慢性阻塞性肺疾病病情判断中的价值[J].肠外与肠内营养杂志,2024,(05):288-292.[doi:DOI : 10.16151/j.1007-810x.2024.05.006]
　CHEN Ai-min,WANG Lei,GAO Ya,et al.The study on the value of geriatric nutritional risk index to assess theseverity of elderly patients with chronic obstructive pulmonary disease[J].PARENTERAL & ENTERAL NUTRITION,2024,(05):288-292.[doi:DOI : 10.16151/j.1007-810x.2024.05.006]
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老年营养风险指数在老年慢性阻塞性肺疾病病情判断中的价值()
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2024年05期
页码:
288-292
栏目:
论著
出版日期:
2024-10-10

文章信息/Info

Title:
The study on the value of geriatric nutritional risk index to assess theseverity of elderly patients with chronic obstructive pulmonary disease
作者:
陈爱民; 王 磊; 高 雅; 姚荣翔
黄山首康医院老年科，安徽黄山245000
Author(s):
CHEN Ai-min;  WANG Lei;  GAO Ya;  YAO Rong-xiang
Department of Gerontology, Huangshan Shoukang Hospital ,Huangshan 245000, Anhui China
关键词:
慢性阻塞性肺疾病 ; 老年 ; 营养评价 ; 老年营养风险指数 ; 预后
Keywords:
Chronic obstructive pulmonary disease;  Elderly patients;  Nutritional assessment;  Geriatricnutritional risk index;  Value prognosis
分类号:
R563
DOI:
DOI : 10.16151/j.1007-810x.2024.05.006
文献标志码:
A
摘要:
目的：探讨常用的营养评价指标在老年慢性阻塞性肺疾病（COPD）病人病情判断中的价值。 方法：回顾性分析 2018 年 1 月至 2020 年 8 月在黄山首康医院老年科住院的 94 例老年 COPD 病人的临床资料，按转归分为好转组（n = 83）和转 ICU 组（n = 11）。评估营养状况和肺功能，收集第 1 秒用力呼气容积（FEV1）占预计值的百分比（FEV1/预计值%）等信息，分析病人入院时的身体质量指数（BMI）、白蛋白、前白蛋白、视黄醇结合蛋白、淋巴细胞计数和老年营养风险指数（GNRI）等营养评价指标与肺功能的相关性，以及上述指标预测病人转入 ICU 的判断价值。 结果：94 例病人中男性 60 例，女性 34 例，中位年龄 78（72, 83）岁。FEV1/预计值%与 BMI、白蛋白、前白蛋白、视黄醇结合蛋白、淋巴细胞计数和 GNRI 等营养评价指标的相关系数分别是 0.535（P < 0.001）、0.726（P < 0.001）、0.351（P = 0.001）、0.498（P < 0.001）、0.572（P < 0.001）和 0.940（P < 0.001）。上述指标预测病人转入 ICU 的受试者操作特征曲线的曲线下面积分别是 0.744(95%CI: 0.544 ~ 0.944, P < 0.001)、0 .834(95% CI: 0.669 ~ 1.000, P <0.001)、0.658(95% CI: 0.468 ~ 0.823, P < 0.001)、0.602(95% CI: 0.408 ~ 0.811, P < 0.001)、0.649(95% CI:0.428 ~0.856, P < 0.001)、0.875(95% CI: 0.751 ~ 0.999, P < 0.001)。 结论：营养评价指标与老年 COPD 病人肺功能有一定的相关性，可协助判断 COPD 病人预后，其中 GNRI 的预测效果最佳。
Abstract:
Objective: To explore the value of common nutritional indexes to assess the severity of elderlypatients with chronic obstructive pulmonary disease (COPD). Methods: The data of 94 elderly COPD patients whowere hospitalized in the Department of Internal Medicine of Huangshan Shoukang Hospital from January 2018 to August2020 were retrospectively analyzed. According to the final outcome of the patients, the patients were divided intoimprovement group (n = 83) and ICU group (n = 11). The nutritional status and lung functions of patients were assessed.Data including forced expiratory volume in one second/prediction (FEV1/Pre) was collected. The correlation of levels ofbody mass index (BMI), albumin, prealbumin, retinol binding protein, lymphocyte count, and geriatric nutritional riskindex with FEV1/Pre was analyzed. And the value of these indexes in predicting whether patients needed to betransferred to ICU or not was analyzed. Results: Among the 94 patients, 60 were male and 34 were female. The ageranged from 50 to 92 years old, and the quartile was 78 (72,83) years old. The correlation coefficients between FEV1/Preand levels of BMI, albumin, prealbumin, retinol binding protein, lymphocyte count, and geriatric nutritional risk indexwere 0.535 (P < 0.001), 0.726 (P < 0.001), 0.351 (P = 0.001), 0.498 (P < 0.001), 0.572 (P < 0.001), and 0.940 (P <0.001), respectively. The areas under the ROC curve predicted by levels of BMI, albumin, prealbumin, retinol bindingprotein, lymphocyte count, and geriatric nutritional risk index were 0.744 (95%CI: 0.544～0.944, P < 0.001), 0.834(95%CI: 0.669～1.000, P < 0.001), 0.658(95%CI: 0.468 ~ 0.823, P < 0.001), 0.602(95%CI: 0.408 ~ 0.811, P < 0.001),0.649(95%CI: 0.428 ~ 0.856, P < 0.001), and 0.875(95%CI: 0.751 ~ 0.999, P < 0.001) , respectively. Conclusions:Levels of BMI, prealbumin, retinol binding protein, lymphocyte count, and geriatric nutritional risk index had certaincorrelation with the severity of COPD, which could be used to assess the severity of COPD. The elderly nutritional riskindex showed the best prediction value.

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备注/Memo

备注/Memo:
作者简介 ：陈爱民，主治医师，从事老年医学方面工作。E-mail：695948529@qq.com通讯作者 ：王 磊，E-mail：30390063@qq.com
更新日期/Last Update: 1900-01-01