[1]于宽勇,匡荣康,杨海涛,等.老年营养风险指数对老年胃癌病人术后手术部位感染的预测价值[J].肠外与肠内营养杂志,2023,(04):221-225.[doi:DOI : 10.16151/j.1007-810x.2023.04.005]
　YU Kuan-yong,KUANG Rong-kang,YANG Hai-tao,et al.Predictive value of senile nutritional risk index for postoperative surgicalsite infection in elderly patients with gastric cancer[J].PARENTERAL & ENTERAL NUTRITION,2023,(04):221-225.[doi:DOI : 10.16151/j.1007-810x.2023.04.005]
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老年营养风险指数对老年胃癌病人术后手术部位感染的预测价值()
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《肠外与肠内营养》杂志[ISSN:1007-810X/CN:32-1477/R]

卷:
期数:
2023年04期
页码:
221-225
栏目:
论著
出版日期:
2023-08-10

文章信息/Info

Title:
Predictive value of senile nutritional risk index for postoperative surgicalsite infection in elderly patients with gastric cancer
作者:
于宽勇; 匡荣康; 杨海涛; 冯文军; 曹传扬; 刘力杨; 强光辉
南京江北医院普通外科，江苏南京210048
Author(s):
YU Kuan-yong;  KUANG Rong-kang;  YANG Hai-tao;  FENG Wen-jun;  CAO Chuan-yang;  LIU Liyang;  QIANG Guang-hui
Department of General Surgery, Nanjing Jiangbei Hospital, Nanjing 210048, Jiangsu, China
关键词:
老年营养风险指数 ; 胃癌根治术 ; 手术部位感染 ; 预测价值
Keywords:
Geriatric nutritional risk index;  Radical gastrectomy;  Surgical site infection;  Predictive value
分类号:
R619，R459.3
DOI:
DOI : 10.16151/j.1007-810x.2023.04.005
文献标志码:
A
摘要:
目的：分析老年营养风险指数(GNRI)对接受择期胃癌根治术的老年病人术后手术部位感染(SSI)的预测价值。 方法：回顾性收集南京江北医院普外科 2015 年 9 月至 2022 年 10 月接受择期胃癌根治术的 235 例老年胃癌病人的临床资料。根据术后是否发生 SSI 将其分为感染组和对照组，通过单因素和多因素分析评价老年胃癌病人术后 SSI 的风险因素，并通过受试者操作特征曲线（ROC）评价 GNRI 对 SSI 的预测价值。 结果：35 例病人术后出现 SSI，其中浅部切口感染 9 例，深部切口感染 11 例，器官（腔隙）感染 15 例，感染率为 14.89%，切口微生物培养以金黄色葡萄球菌、大肠埃希菌为主。单因素分析显示，低 GNRI、低 BMI、低白蛋白水平、手术持续时间长与 SSI 相关。多因素分析显示手术持续时间长和低 GNRI 是预测术后 SSI 的独立危险因素。ROC 曲线分析显示，术前低GNRI 对术后 SSI 的发生具有良好的预测价值（曲线下面积 = 0.837，灵敏度 82.86%，特异度 74.50%，最佳截止值为96.35）。 结论：GNRI 是一种简单有效的预测老年胃癌病人术后 SSI 的临床指标，具有较高的临床应用价值。
Abstract:
Objective: To evaluate the predictive value of Geriatric nutritional risk index (GNRI) in postoperativesurgical site infection (SSI) in elderly patients undergoing elective radical gastrectomy. Methods: The clinical data of235 elderly patients with gastric cancer who received selective radical gastrectomy in general Surgery Department of ourhospital from September 2015 to October 2022 were retrospectively collected. The patients were divided into infectiongroup and control group according to whether SSI occurred after surgery. The risk factors of postoperative SSI in elderlypatients with gastric cancer were evaluated by univariate and multivariate analysis, and the predictive value of GNRI onSSI was evaluated by receiver operating characteristic curve (ROC). Results: SSI occurred in 35 patients after surgery,including 9 cases of superficial incision infection, 11 cases of deep incision infection, and 15 cases of organ (lacunar)infection, the infection rate was 14.89%. Staphylococcus aureus and Escherichia coli were the main microorganismscultured in the incision. Univariate analysis showed that low GNRI, low BMI, low albumin levels, and long duration ofsurgery were associated with SSI. Multivariate analysis showed that long duration of surgery and low GNRI wereindependent risk factors for predicting postoperative SSI. ROC curve analysis showed that preoperative low GNRI hadgood predictive value for postoperative SSI occurrence (area under curve = 0.837, sensitivity 82.86%, specificity74.50%, optimal cutoff value 96.35). Conclusion: GNRI is a simple and effective clinical indicator for predictingpostoperative SSI in elderly patients with gastric cancer, and has high clinical application value.

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备注/Memo

备注/Memo:
基金项目 ：南京市卫生科技发展发专项资金（YKK18241）作者简介 ：于宽勇，住院医师，医学硕士，从事肝胆胃肠方向临床研究。E-mail：511528078@qq.com通讯作者 ：强光辉，E-mail：guanghqiang @126.com
更新日期/Last Update: 1900-01-01